Viagra is a successful first-line therapy for ED treatment for most men. Still some serious side effects possibility can prevent certain groups of men from taking it. One of the possible serious side effects of Viagra is ocular effect. These are increased light sensitivity, blurring, and a bluish tint or haze to vision.
Some men are more likely to get ocular side effects due to their eye problems or diseases such as macular degeneration, diabetic retinopathy, retinitis pigmentosa or other retinal disease. These patients are usually recommended to avoid Viagra use.
Viagra may cause ocular side effects in men who take larger doses of the drug. Vision side effects are usually dose-related, so the larger the dosage, the more chance of the risk. According to one of the clinical Viagra study about 50 percent of men taking 200 mg of Viagra experience vision changes. Therefore men should not exceed the max recommended dose of 100 mg per day. Those who are recommended to use lower doses of Viagra should never take larger doses of this drug.
Viagra produces vision changes because it inhibits phosphodiesterase enzymes including an enzyme PDE6 which is present in retinal photoreceptors. Though Viagra has a mild inhibiting effect on this enzyme (it is selective for PDE5) it can cause increased light sensitivity and so called blue vision.
Retinal specialists warn men with retinal problems not to take Viagra. Patients with eye conditions should consult their doctors before using this drug.
A recent study, the results of which were published in the Journal of Sexual Medicine detected that a chronic infection of the gums called periodontitis may lead to erectile problems.
The researchers from China’s Luzhou Medical College observed that animals with chronic gum infectious diseases had less of the enzyme significant for erectile process – eNOS. The researchers from China investigated the results of the other study which found that gum infections are commonly met in men with ED problems than in men without them.
Gum diseases are inflammatory diseases and may influence on the development of ED, still more studies are needed to discover the links between periodontal and penile health.
The researchers suggest that gum disease may be a sign of diabetes, heart disease, and malnutrition which in their turn affect male potency.
A new research published in the British Journal of Urology International suggests that using too many drugs regularly may lead to erectile problems in men of different ages.
Researchers surveyed more than 37,000 males in the ages of 50 and 70, and investigated that erectile dysfunction was met more often among men taking many different medications for different conditions they had. According to the findings of this study the more meds a person takes the more chance of ED development he has
Many men take various medications for different conditions even if there is no urgent necessity in it. The researchers found that 57 % of study participants took more than 3 medications. It was estimated that 25 % of the participants used at least 10 medications on a regular basis.
The most common medications related to impotence are medications for hypertension management and antidepressant medications. If you experience ED and take many different medications, ask doctor about side effects of the medications you take and if they exist what other treatment opts are available.
Viagra cardiac effects were evaluated in an open-label, uncontrolled, pilot study. The test participants received single oral doses of sildenafil up to 100 mg. The doses of the drug produced no clinically meaningful changes in the ECGs of normal males.
The eight patients taking part in this small pilot study were diagnosed with stable ischemic heart disease and underwent Swan-Ganz catheterization. They were administered a total dose of 40 mg Sildenafil by four intravenous infusions.
The study observed that the mean resting systolic and diastolic blood pressures reduced by 7% and 10% in comparison with the initial parameters in these males. Mean resting parameters for artery pressure, pulmonary artery pressure, pulmonary artery occluded pressure and cardiac output reduced by 28%, 28%, 20% and 7% respectively.
The total dosage (40 mg) of Sildenafil caused higher plasma concentrations – 2 to 5 times higher than the max plasma levels following a single oral dose of 100 mg in healthy males. Besides, the hemodynamic response to exercise endurance was preserved in the patients with cardiovascular disease.
A double-blind study involved more than 140 males with ED who were diagnosed with chronic stable exercise-induced angina not receiving regularly oral nitrates, were randomized to a single dose of placebo or Viagra 100 mg 1 hour prior to exercise testing. The main thing to evaluate was time to registering angina in the evaluable cohort. The mean times to beginning of the limiting angina were 423.6 and 403.7 seconds for sildenafil (N=70) and placebo, accordingly. These findings proved that the cardiac effect of Viagra was clinically the same as placebo.
Stress is a normal part of our regular life. Every one of us feels stress and reacts to it. Still a modern man experiences more stress because of job, family problems, death of a family member, legal problems, divorce, and other things. If stress is constant it affects our body negatively and problems, like diabetes, depression, sleep and eating disorders and erectile dysfunction can occur. When it is impossible to prevent stress, you should learn to manage and reduce it.
Here are some tips helping to reduce and cope with stress:
• If you need help ask others to assist you.
• Take responsibility for the situation.
• Try to solve your problems as soon as possible, do not delay them for later solving.
• Discuss your problems with your family or relatives, with anyone who can understand and support you.
• Try to express your feelings, do not keep your emotions.
• Try to eliminate the cause of stress or avoid it if possible.
• Relax and get enough rest.
• Eat and drink normally.
• Quit smoking and drinking alcohol.
• Get regular exercises.
Managing stress is a regular thing to do. Try to find your own strategies of stress coping. In case you cannot manage stress yourself, ask for help.
Can stress be the cause for erectile problems in men? One study placed high psychological stress right with hypertension and other conditions as a risk factor. Other studies have suggested that men with impotence experience greater stress levels.
Stress related to family problems and job-related stresses are among the most dangerous for erectile function. Stress invades into our sexual life and violates sexual function both in the short and long terms:
1. Stress affects the testosterone level, and lower testosterone impairs internal penile tissues, and thus reduces nitric oxide levels. This results in arterial plaque buildup in penile arteries.
2. Lots of studies suggest that stress may cause heart disease and other related disorders. Heart disease is proven to be one of the direct afflictions of impotence. Ongoing work stress may result in poor lifestyle habits and behaviors, such as smoking, excessive drinking, absence of physical activity and erectile dysfunction harmful to both heart and penis.
3. Stress increases the level of cortisol which is bad for erections, its increased levels are related to insulin resistance and decreased nitric oxide.
4. An increased visceral fat is also associated with stress. This fat usually accumulates in the abdominal area and is often called “beer belly”. It is a very bad factor influencing on erectile function. Abdominal fat is most dangerous form of body fat because it increases the risk for cardiovascular disease, stroke and Alzheimer’s disease.
5. Obesity and overweight may be the direct result of chronic psychological stress. Stressed people eat more than usual and eat practically all the time whether they are hungry or not.
It is absolutely necessary to cope with stress and stressful situations by your own or with the help of your relatives or family. If you cannot manage stress yourself seek special medical help.
Viagra has become largely popular among young men. This drug due to its ability of ED treating resulted in increased recreational use. Though researches on Viagra’s recreational use are not enough, the experts suggest that Sildenafil has lower or no efficacy when taken by healthy men who do not have erectile dysfunction. The studies were little, still one study demonstrated that a 25 mg dose of Viagra caused minor alterations or improvements in erectile function. The medication taken with recreational purpose has reducing effect on the time of “recovery” – the time after erection (refractory period).
Besides recreational use, Viagra is sometimes taken by the athletes who wish to improve their physical abilities and athletic performance. Viagra is used by many athletes for their sports results enhancements; athletes use Viagra to open blood vessels to enlarge their muscles, to concentrate oxygen and thus improve the performance.
Though many people think that Viagra is safe and effective in its different uses, Viagra should be taken only by men who are diagnosed with ED and really need it, others should not use this prescription medication.
According to the new study held in South Korea lots of oral medications for impotence treatment sold online are contaminated and do not work. But the most dangerous thing is that such medications may contain too much of the main component. It is especially insecure for the patients with hypertension and heart disease, because taking such medications may lead to life-threatening effects.
The study shows that there lots of facts that many drugs you purchase online or offline in non-registered pharmacies are cheaper, but usually they are faked.
Impotence drugs belong to the special class of drugs which open the intimate nature of the difficulty that men experience that is why most men are hesitant to discuss it with a doctor. Men having ED often try things which can be risky or dangerous for health. They try drugs that look like brands or claimed to be working as brands.
In the Korean study 19 faked ED drugs were compared with brands including Viagra and Cialis. One third of the faked drugs were different in size and about 40% differ in color. More than 55% of the fakes had too much of the main component and about 3 % of them had no active component at all. Besides, practically all fakes had in their formulas ingredients that are not authorized or approved.
These facts and figures should be taken into consideration by the people who order drugs online. Actually only your doctor’s consultation will help you to avoid unpleasant situations and eliminate the possibility to buy drugs which are not proven or authorized to treat ED in men.
Nowadays the practice of purchasing ED or any other medications online has become a part of our everyday life- it is very convenient to sell and buy in the internet especially medications which are available in local pharmacies only with a prescription.
Many men buy such medications as Viagra, Cialis or Levitra and many other alternatives on the web. Most of the consumers do not even think about the dangers that these medications may hide. Experts in pharmacology warn about the frequencies of buying counterfeit medications for ED problem online.
The main danger is that such medications may contain too much of the active component or do not contain it at all. These medications may be extremely dangerous for those patients who have other serious conditions – hypertension, heart disorder or kidney disease. Lots of pharmacies online offer ED medications at reduced prices, but they appear to be fakes which do not work.
The most important thing you should remember before buying online is to get the information about the web site which is selling the medications, to find out if the online pharmacy is legal and can carry out its activities.
Please, be careful when you choose online pharmacy.
A new study involving couples in which both partners were older than 57 years of old was conducted to estimate how specific relationship problems may influence the sexual life of both partners and particularly man’s ability to get an erection.
The study’s finding were surprising because it showed that older men had negative attitude to close friendship of their wives or partners with other men. And this friendship may affect older man’s performance in the bed and even cause problems with erections.
Besides, these older men tend to have difficulty achieving orgasm during sex. The study compared couples where there’s such situation of close friendship with other men and couples who didn’t communicate so often with his or her friends.
Old men often think that their sexual partners discuss private sexual relations with other men. This may lead to stress, depression, low self esteem and erectile dysfunction.
Frequently such old men experience feelings of being not attractive to their sexual partners and suffer from misunderstanding in silence. So the study concluded that it is very important to communicate openly with your sexual partner and try to understand his or her needs and concerns.